43rd
ISICEM

International symposium on intensive care & emergency medicine

March 19-22, 2024

Brussels Congress Center, Brussels

Interactive program

Tuesday 19 March 2024

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            Standard presentation Gold Hall Morning (CET)

            OPENING

            Moderator(s):  Derek C  Angus (Pittsburgh, United States)
Elie Azoulay (Paris, France)

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    Welcome

                Fabio S Taccone (Brussels, Belgium)

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    Report of the Round Table Conference - Artificial intelligence in acute medicine

                Azra Bihorac (Gainesville, United States)

                Maurizio  Cecconi (Milan, Italy)

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    Max Harry Weil lecture: Does evidence based medicine limit the practice of personalized medicine?

                Sharon Einav-Bromiker (Tel Aviv Jaffo, Israel)

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    Let us make a green ICU

                Nicole Hunfeld (Rotterdam, Netherlands)

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    Host gene expression signatures in children evaluated for sepsis

                Luregn Schlapbach (Zürich, Switzerland)

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    Effect of lower vs higher oxygenation targets: experience in COVID-19

                Frederik Nielsen (Aalborg, Denmark)

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    Individualized oxygen targets in mechanically ventilated adults

                Kevin Buell (Chicago, United States)

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    Safe application of early active mobilisation

                Michelle Paton (Clayton, Australia)

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            Standard presentation Gold Hall Morning (CET)

            EXTRACORPOREAL CO2 REMOVAL

            Moderator(s):  Heatherlee Bailey (Durham, United States)
Alain Combes (Paris, France)

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    What we have learned so far

                Luciano Gattinoni (Göttingen, Germany)

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    ECCO2R in ARDS

                Luigi Camporota (London, United Kingdom)

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    ECCO2R in COPD

                V Marco Ranieri (Bologna, Italy)

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    Failure of ECCO2R is a failure of technology

                Laurent Brochard (Toronto, Canada)

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    Discussion

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            Standard presentation Gold Hall Afternoon (CET)

            ARTIFICIAL INTELLIGENCE - PRINCIPLES

            Moderator(s):  Mypinder S Sekhon (Vancouver, Canada)
Christopher Seymour (Pittsburgh, United States)

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    Building efficient data driven research

                Mauro Oddo (Lausanne, Switzerland)

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    Challenges in data collection in the ICU

                Leo Anthony Celi (Cambridge, United States)

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    Getting into DataScience

                Ari Ercole (Cambridge, United Kingdom)

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    Discussion

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    Natural language processing applied to delirium

                Rinaldo Bellomo (Melbourne, Australia)

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    Natural Language Processing in Critical Care

                Benjamin Shickel (Gainsville, United States)

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    Primer on large language models and prompt engineering

                Azra Bihorac (Gainesville, United States)

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    Discussion

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    Sharing is caring - ICUs should share their big data

                Paul Elbers (Amsterdam, Netherlands)

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    Understanding machine learning methods

                Edward Schenck (New York, United States)

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    Bridging the ´byte to bedside` gap

                Matthieu Komorowski (London, United Kingdom)

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    Discussion

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            Standard presentation Gold Hall Afternoon (CET)

            CARDIOGENIC SHOCK

            Moderator(s):  Sharon Einav-Bromiker (Tel Aviv Jaffo, Israel)
Giovanni Landoni (Milan, Italy)

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    After cardiac arrest

                Markus Skrifvars (Helsinki, Finland)

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    The ´congestive heart failure` entity is outdated

                Anthony  McLean (Sydney, Australia)

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    Fulminant myocarditis

                Matthieu Schmidt (Paris, France)

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    Management of postoperative myocardial injury

                Michelle Chew (Linköping, Sweden)

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    Discussion

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    When to consider ECMO

                Jan Belohlavek (Prague, Czech Republic)

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    VA-ECMO followed by heart transplantation?

                Alain Combes (Paris, France)

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    Management of renal failure

                Stéphane Gaudry (Bobigny, France)

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    Mechanical support

                Susanna  Price (London, United Kingdom)

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    Discussion

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            Standard presentation Copper Hall Morning (CET)

            ENDOTHELIAL PROTECTION

            Moderator(s):  Paul Elbers (Amsterdam, Netherlands)
Despoina  Koulenti (London, United Kingdom)

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    How to assess endothelial damage

                Jan Bakker (New York, United States)

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    Gut permeability in sepsis

                Craig M Coopersmith (Atlanta, United States)

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    Therapies to improve endothelial cell function

                Peter Pickkers (Nijmegen, Netherlands)

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    Plasma as a resuscitation fluid?

                Nicole Juffermans (Amsterdam, Netherlands)

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    Discussion

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            Standard presentation Copper Hall Afternoon (CET)

            SEPSIS: BACK TO BASICS

            Moderator(s):  Lennie Derde (Utrecht, Netherlands)
Frank van Haren (Sydney, Australia)

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    Current thinking on the pathogenesis of sepsis

                Joost Wiersinga (Amsterdam, Netherlands)

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    Reprogramming metabolism to survive sepsis

                Hernando Gomez (Pittsburgh, United States)

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    What do we mean by ´dysregulated immune response`?

                Manu Shankar–Hari (Edinburgh, United Kingdom)

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    Discussion

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    Understanding the neutrophil

                John C Marshall (Toronto, Canada)

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    New insights into thermoregulation

                Peter Pickkers (Nijmegen, Netherlands)

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    The influence of alcohol

                Craig M Coopersmith (Atlanta, United States)

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    Discussion

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    How circadian rhythms impact host responses

                Elizabeth Wilcox (Edmonton, Canada)

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    The important role of the microbiome in sepsis

                Joost Wiersinga (Amsterdam, Netherlands)

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    We could use immune dysregulation scores

                Tom van der Poll (Amsterdam, Netherlands)

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    Discussion

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            Standard presentation Copper Hall Afternoon (CET)

            THE RENIN-ANGIOTENSIN SYSTEM IN THE ICU

            Moderator(s):  Beverley Hunt (London, United Kingdom)
Manu Shankar–Hari (Edinburgh, United Kingdom)

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    How the renin-angiotensin system is affected

                Matthieu Legrand (San Francisco, United States)

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    How we can manipulate it in critical care

                Filippo Annoni (Brussels, Belgium)

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    Is renin the new lactate?

                Ashish K Khanna (Winston-Salem, United States)

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    The future place of angiotensin II

                Rinaldo Bellomo (Melbourne, Australia)

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    Discussion

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            Standard presentation Silver Hall Morning (CET)

            FLUID REMOVAL

            Moderator(s):  Paul H Mayo (New York, United States)
Axel Nierhaus (Hamburg, Germany)

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    Forget about wet or dry!

                Daniel  De Backer (Braine l´Alleud, Belgium)

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    The limits of diuretic therapy

                Marlies Ostermann (London, United Kingdom)

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    Optimal ultrafiltration

                Jean-Louis Vincent (Brussels, Belgium)

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    Fluid removal in heart failure

                Stéphane Gaudry (Bobigny, France)

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    Discussion

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            Standard presentation Silver Hall Afternoon (CET)

            PEEP OPTIMIZATION

            Moderator(s):  Jeremy Beitler (New York, United States)
Leo Heunks (Nijmegen, Netherlands)

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    Should we first assess recruitability?

                Luciano Gattinoni (Göttingen, Germany)

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    Above the airway opening pressure

                Michel  Slama (Amiens, France)

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    Using EIT

                Laurent Brochard (Toronto, Canada)

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    Driving pressure

                Ewan Goligher (Toronto, Canada)

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    Discussion

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    Esophageal pressure

                Lise  Piquilloud (Lausanne, Switzerland)

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    Don´t forget the RV

                Antoine Vieillard–Baron (Boulogne-Billancourt, France)

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    … and the LV

                Michel  Slama (Amiens, France)

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    How to put it all together

                Oriol Roca (Sabadell, Spain)

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    Discussion

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            Standard presentation Silver Hall Afternoon (CET)

            LUNG PROTECTION

            Moderator(s):  Aarti Sarwal (Winston Salem, United States)
Alexander Vlaar (Amsterdam, Netherlands)

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    Finding the optimal tidal volume

                V Marco Ranieri (Bologna, Italy)

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    Driving pressure is more important than tidal volume

                Ewan Goligher (Toronto, Canada)

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    Is it different for spontaneous vs. mechanical ventilation?

                Luciano Gattinoni (Göttingen, Germany)

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    Discussion

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    Detecting end-tidal hyperinflation

                John J Marini (St Paul, United States)

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    The role of PEEP

                Domenico Luca Grieco (Rome, Italy)

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    Rest is best

                Patricia Rocco (Rio De Janeiro, Brazil)

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    Discussion

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            Standard presentation 100 Hall Morning (CET)

            POSTANOXIC BRAIN DAMAGE

            Moderator(s):  Giuseppe Citerio (Monza, Italy)
Mauro Oddo (Lausanne, Switzerland)

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    Limiting oxygen

                Markus Skrifvars (Helsinki, Finland)

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    Moving towards personalized temperature control

                Fabio S Taccone (Brussels, Belgium)

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    We should target neuroinflammation

                Mypinder S Sekhon (Vancouver, Canada)

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    Neuroprognostication : mission (im)possible?

                Cherylee WJ Chang (Durham, United States)

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    Discussion

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            Standard presentation 100 Hall Afternoon (CET)

            BLOOD PURIFICATION IN SEPSIS

            Moderator(s):  Nicole Juffermans (Amsterdam, Netherlands)
Stephen M Pastores (New York, United States)

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    The rationale

                Axel Nierhaus (Hamburg, Germany)

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    The problems

                Christopher Rugg (Innsbruck, Austria)

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    When to combine it with ECMO

                Konstanty Szuldrzynski (Warsaw, Poland)

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    Discussion

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    The right patient

                Gianluca  Villa (Florence, Italy)

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    How biomarkers could help

                Silvia Coelho (Amadora, Portugal)

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    The therapeutic trial we need

                Stéphane Gaudry (Bobigny, France)

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    Discussion

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            Standard presentation 100 Hall Afternoon (CET)

            HOW I IMAGINE THE FUTURE

            Moderator(s):  Elena Bignami (Parma, Italy)
Leo Anthony Celi (Cambridge, United States)

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    Before hospital admission

                Michael R Pinsky (Pittsburgh, United States)

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    The emergency room

                Heatherlee Bailey (Durham, United States)

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    The operating room

                Azra Bihorac (Gainesville, United States)

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    Discussion

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    The ICU

                Maurizio  Cecconi (Milan, Italy)

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    Machine learning systems to inform sepsis resuscitation

                Matthieu Komorowski (London, United Kingdom)

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    Monitoring for organ failure throughout the hospital

                Michelle N Gong (New York, United States)

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    Discussion

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            Pro-con debate 100 Hall Afternoon (CET)

            USE OF VISCOELASTIC TESTING IN MASSIVE BLEEDING 

            Moderator(s):  Tomoko Fujii (Tokyo, Japan)

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    Use of viscoelastic testing in massive bleeding

                PRO: Pierre Bouzat (Grenoble, France)

                CON: Michael Reade (Brisbane, Australia)

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            Standard presentation 400 Hall Afternoon (CET)

            FUNGAL INFECTIONS

            Moderator(s):  Evangelos Giamarellos–Bourboulis (Athens, Greece)
Bhakti Patel (Chicago, United States)

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    Septic shock from candidemia: how often?

                Elie Azoulay (Paris, France)

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    Fungal infection in the ´immunocompetent` patient

                Liesbet De Bus (Ghent, Belgium)

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    Emerging Candida species

                Thierry Calandra (Lausanne, Switzerland)

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    Discussion

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    Antifungal dose adjustments during CRRT

                Patrick Honoré (Yvoir, Belgium)

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    Antimicrobial and antifungal stewardship: are they different?

                Despoina  Koulenti (London, United Kingdom)

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    Biomarkers to guide therapy

                Joost Wiersinga (Amsterdam, Netherlands)

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    Discussion

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            Standard presentation 400 Hall Afternoon (CET)

            UPDATE ON SEPSIS BIOMARKERS

            Moderator(s):  Djillali Annane (Garches, France)
Lieuwe  Bos (Amsterdam, Netherlands)

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    Novel infection diagnostics

                Mervyn Singer (London, United Kingdom)

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    Are they ready for routine use?

                Jan De Waele (Ghent, Belgium)

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    They can help to identify sepsis in the presence of liver failure

                Julia  Wendon (London, United Kingdom)

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    Discussion

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    Bacterial or viral infection: consult the immune response

                Evangelos Giamarellos–Bourboulis (Athens, Greece)

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    Genomic damage signals in sepsis

                Edward Schenck (New York, United States)

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    Novel sepsis markers

                Andrew  Shorr (Potomac, United States)

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    How biomarkers can guide the duration of antimicrobial therapy

                Jan De Waele (Ghent, Belgium)

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    Discussion

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            Standard presentation Panoramic Room Morning (CET)

            EARLY MOBILIZATION

            Moderator(s):  Shawniqua Williams Roberson (Nashville, United States)
Fernando Zampieri (Edmonton, Canada)

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    What is early?

                Bhakti Patel (Chicago, United States)

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    Recent trials showed no benefit

                Leo Heunks (Nijmegen, Netherlands)

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    The effect of exercise dosage on outcomes

                Michelle Paton (Clayton, Australia)

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    Mobilization during ECMO: a bit too much?

                Matthieu Schmidt (Paris, France)

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    Discussion

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            Tutorial Panoramic Room Afternoon (CET)

            HEAT STROKE


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    Heat stroke

                Heatherlee Bailey (Durham, United States)

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            Tutorial Panoramic Room Afternoon (CET)
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    Prescription of antibiotics during CRRT

                Tomoko Fujii (Tokyo, Japan)

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            Standard presentation Panoramic Room Afternoon (CET)

            WORKING TOGETHER

            Moderator(s):  Vincent Liu (Oakland, United States)
Arthur van Zanten (Ede, Netherlands)

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    Optimal organization

                Axel Nierhaus (Hamburg, Germany)

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    The important role of a pharmacist

                Nicole Hunfeld (Rotterdam, Netherlands)

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    How to retain your staff

                Elie Azoulay (Paris, France)

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    How to keep everyone happy

                Julia  Wendon (London, United Kingdom)

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    Discussion

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    How to lead successful rounds

                Craig M Coopersmith (Atlanta, United States)

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    How to learn at the bedside

                Mervyn Singer (London, United Kingdom)

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    How to develop research in the ICU

                Mauro Oddo (Lausanne, Switzerland)

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    Expectations from the new generation

                Sara Crager (Los Angeles, United States)

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    Discussion

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            Pro-con debate Panoramic Room Afternoon (CET)

            MONITORING THE MICROCIRCULATION IN THE SURGICAL PATIENT

            Moderator(s):  Michelle Chew (Linköping, Sweden)

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    Monitoring the microcirculation in the surgical patient

                PRO: Jacques  Duranteau (Le Kremlin-Bicêtre, France)

                CON: Bernd Saugel (Hamburg, Germany)

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            Round table The Arc Room Afternoon (CET)

            PRACTICAL PRONE POSITIONING

            Moderator(s):  Lise  Piquilloud (Lausanne, Switzerland)

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    Practical prone positioning

                Luigi Camporota (London, United Kingdom)

                Giacomo Grasselli (Milan, Italy)

                Matthieu Schmidt (Paris, France)

                Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

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            Round table The Arc Room Afternoon (CET)

            THE NEED TO MONITOR CARDIAC OUTPUT

            Moderator(s):  Jan Bakker (New York, United States)

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    The need to monitor cardiac output

                Daniel  De Backer (Braine l´Alleud, Belgium)

                Xavier Monnet (Le Kremlin-Bicêtre, France)

                Michael R Pinsky (Pittsburgh, United States)

                Bernd Saugel (Hamburg, Germany)

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            Tutorial The Arc Room Afternoon (CET)
  • -

    Pathophysiology of sepsis associated renal failure

                Hernando Gomez (Pittsburgh, United States)

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            Tutorial The Arc Room Afternoon (CET)
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    Pathophysiology of brain trauma

                Marek Mirski (Baltimore, United States)

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            Tutorial The Arc Room Afternoon (CET)
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    Lessons learned from recent trials of ICU nutrition

                Christian Stoppe (Würzburg and Berlin, Germany)

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            Tutorial The Arc Room Afternoon (CET)
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    Intrabdominal compartment syndrome

                Philippe Montravers (Paris, France)

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            Meet the experts Demo box 1 Morning (CET)
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    Everything you´ve always wanted to know about hemodynamic physiology

                Xavier Monnet (Le Kremlin-Bicêtre, France)

                Michael R Pinsky (Pittsburgh, United States)

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            Meet the experts Demo box 1 Morning (CET)
  • -

    Optimal antibiotic therapy

                Maya  Hites (Brussels, Belgium)

                Andrew  Shorr (Potomac, United States)

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            Meet the experts Demo box 1 Afternoon (CET)
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    Withdrawal of life-sustaining therapies in the patient with acute brain injury

                Victoria McCredie (Toronto, Canada)

                Alexis Turgeon (Québec City, Canada)

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            Clinical Challenges Demo box 1 Afternoon (CET)
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    Is this patient brain ´dead`?

                Cherylee WJ Chang (Durham, United States)

                Giuseppe Citerio (Monza, Italy)

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            Demonstration Demo box 1 Afternoon (CET)
  • -

    Urgent echo in cardiogenic shock

                Anthony  McLean (Sydney, Australia)

                Susanna  Price (London, United Kingdom)

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            Clinical Challenges Demo box 1 Afternoon (CET)
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    How would you act with no monitoring device?

                Xavier Monnet (Le Kremlin-Bicêtre, France)

                Sheila N Myatra (Mumbai, India)

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            Demonstration Demo box 1 Afternoon (CET)
  • -

    Measurement of mean systemic filling pressure at the bedside

                Paul H Mayo (New York, United States)

                Michael R Pinsky (Pittsburgh, United States)

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            Meet the experts Demo box 2 Morning (CET)
  • -

    Appropriate use of novel antifungal agents

                Thierry Calandra (Lausanne, Switzerland)

                Philippe Montravers (Paris, France)

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            Demonstration Demo box 2 Morning (CET)
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    How to assess arterial tone at the bedside

                Michael R Pinsky (Pittsburgh, United States)

                Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

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            Case discussion Demo box 2 Afternoon (CET)
  • -

    What hemodynamic monitoring in this patient?

                Xavier Monnet (Le Kremlin-Bicêtre, France)

                Bernd Saugel (Hamburg, Germany)

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            Meet the experts Demo box 2 Afternoon (CET)

            HOW TO FEED


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    How to feed

                Jan Gunst (Leuven, Belgium)

                Emma Ridley (Melbourne, Australia)

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            Meet the experts Demo box 2 Afternoon (CET)
  • -

    Extubation failure in the ICU

                Domenico Luca Grieco (Rome, Italy)

                Arnaud Thille (Poitiers, France)

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            Case discussion Demo box 2 Afternoon (CET)
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    Optimal blood pressure in stroke

                Jacques  Duranteau (Le Kremlin-Bicêtre, France)

                Alexis Turgeon (Québec City, Canada)

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            Meet the experts Demo box 2 Afternoon (CET)
  • -

    The dying process

                Victoria Metaxa (London, United Kingdom)

                Jean-Louis Vincent (Brussels, Belgium)

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            Meet the experts Demo box 3 Afternoon (CET)
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    Coping with resistant bacteria

                Despoina  Koulenti (London, United Kingdom)

                Andrew  Shorr (Potomac, United States)

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            Clinical Challenges Demo box 3 Afternoon (CET)
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    Why does this patient with cancer develop renal failure

                Victoria Metaxa (London, United Kingdom)

                Marlies Ostermann (London, United Kingdom)

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            Case discussion Demo box 3 Afternoon (CET)
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    A patient with refractory intracranial hypertension

                Michael Reade (Brisbane, Australia)

                Fabio S Taccone (Brussels, Belgium)

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            Case discussion Demo box 3 Afternoon (CET)
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    ARDS in a TBI patient

                Chiara Robba (Genoa, Italy)

                Fabio S Taccone (Brussels, Belgium)

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            Case discussion Demo box 3 Afternoon (CET)
  • -

    A patient with severe hypoxemia in the absence of ECMO

                V Marco Ranieri (Bologna, Italy)

                Oriol Roca (Sabadell, Spain)

Wednesday 20 March 2024

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            Standard presentation Gold Hall Morning (CET)

            ARTIFICIAL INTELLIGENCE - APPLICATIONS

            Moderator(s):  Rinaldo Bellomo (Melbourne, Australia)
Azra Bihorac (Gainesville, United States)

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    Dynamic individualised prediction

                Ari Ercole (Cambridge, United Kingdom)

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    AI for continuous acuity prediction in the ICU

                Benjamin Shickel (Gainsville, United States)

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    Prognostication: we can do better than scores

                Massimiliano Greco (Milan, Italy)

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    Discussion

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    AI for all in sepsis?

                Christopher Seymour (Pittsburgh, United States)

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    AI for early sepsis detection: A word of caution

                Joost Wiersinga (Amsterdam, Netherlands)

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    AI for expert clinical support.

                Hernando Gomez (Pittsburgh, United States)

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    Discussion

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    AI in neurocritical care

                Soojin Park (New York, United States)

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    AI in perioperative medicine

                Elena Bignami (Parma, Italy)

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    Is AI the new ICU resident?

                Geert  Meyfroidt (Leuven, Belgium)

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    Building workforce capacity to integrate it into practice

                Vincent Liu (Oakland, United States)

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    Discussion

  • -

    The interface of AI and RCTs

                Derek C  Angus (Pittsburgh, United States)

  • -

    Building capacity in AI among the next generation of ICU clinicians

                Leo Anthony Celi (Cambridge, United States)

  • -

    We must stay in control

                Sharon Einav-Bromiker (Tel Aviv Jaffo, Israel)

  • -

    … however the staff numbers will be affected

                Paul Elbers (Amsterdam, Netherlands)

  • -

    Discussion

-
            Plenary lecture Gold Hall Morning (CET)
  • -

    Disseminated intra-vascular coagulation: an update

                Jerrold Levy (Durham, United States)

-
            Standard presentation Gold Hall Afternoon (CET)

            IMPROVING VASOPRESSOR USE

            Moderator(s):  Djillali Annane (Garches, France)
Susanna  Price (London, United Kingdom)

  • -

    When is arterial pressures too low?

                Marek Mirski (Baltimore, United States)

  • -

    Early administration of norepinephrine in patients with septic shock: yes, but why?

                Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

  • -

    What about vasopressin?

                Jacques  Duranteau (Le Kremlin-Bicêtre, France)

  • -

    What about angiotensin-II?

                Giovanni Landoni (Milan, Italy)

  • -

    Discussion

  • -

    Vasopressin and/or angiotensin-II: a practical approach

                Arthur van Zanten (Ede, Netherlands)

  • -

    Would a venous vasopressor benefit?

                Ashish K Khanna (Winston-Salem, United States)

  • -

    Don´t forget the heart

                Michel  Slama (Amiens, France)

  • -

    Discussion

-
            Standard presentation Gold Hall Afternoon (CET)

            ULTRASOUND

            Moderator(s):  Marc  Maegele (Cologne, Germany)
Michael Reade (Brisbane, Australia)

  • -

    Resuscitation

                Aarti Sarwal (Winston Salem, United States)

  • -

    Brain

                Fabio S Taccone (Brussels, Belgium)

  • -

    Heart

                Antoine Vieillard–Baron (Boulogne-Billancourt, France)

  • -

    Abdomen

                Pierre Bouzat (Grenoble, France)

  • -

    Discussion

  • -

    Lung

                Paul H Mayo (New York, United States)

  • -

    Lung ultrasound for phenotyping of ARDS

                Lieuwe  Bos (Amsterdam, Netherlands)

  • -

    ´Ultranurse`: teaching point of care ultrasound to ICU nurses

                Paul Elbers (Amsterdam, Netherlands)

  • -

    Discussion

-
            Standard presentation Copper Hall Morning (CET)

            SEPSIS MANAGEMENT

            Moderator(s):  Philippe Montravers (Paris, France)
Mervyn Singer (London, United Kingdom)

  • -

    Phoenix sepsis criteria: small or big step forward?

                Luregn Schlapbach (Zürich, Switzerland)

  • -

    Early risk assessment

                Evangelos Giamarellos–Bourboulis (Athens, Greece)

  • -

    Should fever be treated?

                Frank van Haren (Sydney, Australia)

  • -

    Source control at 4 am rather than 8 am

                Jan De Waele (Ghent, Belgium)

  • -

    Artificial intelligence in infection management

                Thierry Calandra (Lausanne, Switzerland)

  • -

    Discussion

  • -

    Artificial intelligence in cardiorespiratory resuscitation

                Michael R Pinsky (Pittsburgh, United States)

  • -

    Past history of heart failure: does it matter?

                Christopher Seymour (Pittsburgh, United States)

  • -

    The importance of left and right ventricular functions

                Michelle Chew (Linköping, Sweden)

  • -

    Beta-stimulation vs. beta-blockade

                Michel  Slama (Amiens, France)

  • -

    Challenges in resource-limited settings

                Sheila N Myatra (Mumbai, India)

  • -

    Discussion

  • -

    Break

-
            Plenary lecture Copper Hall Morning (CET)
  • -

    Update on paediatric critical care trials

                Luregn Schlapbach (Zürich, Switzerland)

-
            Standard presentation Copper Hall Afternoon (CET)

            OPTIMIZING ANTIBIOTIC THERAPY

            Moderator(s):  Julie Helms (Strasbourg, France)
Christian Stoppe (Würzburg and Berlin, Germany)

  • -

    New guidelines

                Mervyn Singer (London, United Kingdom)

  • -

    Antibiotic stewardship should be improved in the emergency room

                Heatherlee Bailey (Durham, United States)

  • -

    Optimal empirical antimicrobial therapy

                Liesbet De Bus (Ghent, Belgium)

  • -

    Discussion

  • -

    Multiresistant pathogens: the optimal strategy

                Philippe Montravers (Paris, France)

  • -

    Continuous infusion of betalactam antibiotics – finally there?

                Jan De Waele (Ghent, Belgium)

  • -

    What about meropenem infusions?

                Maya  Hites (Brussels, Belgium)

  • -

    Discussion

  • -

    Antibiotics – for how long?

                Joost Wiersinga (Amsterdam, Netherlands)

  • -

    Early switch to oral antibiotics is the way to go

                Thierry Calandra (Lausanne, Switzerland)

  • -

    Novel antibiotics in the ICU

                Andrew  Shorr (Potomac, United States)

  • -

    Discussion

  • -

    Upsurge in invasive group A streptococcal infections

                Maya  Hites (Brussels, Belgium)

  • -

    Multiresistant pathogens: have we already entered the post-antibiotic era?

                Despoina  Koulenti (London, United Kingdom)

  • -

    SDD: Dutch hobby or standard of care?

                Lennie Derde (Utrecht, Netherlands)

  • -

    SDD does improve outcomes

                Jan De Waele (Ghent, Belgium)

  • -

    Discussion

-
            Standard presentation Silver Hall Morning (CET)

            SHOCK: THE BASICS

            Moderator(s):  Anthony  McLean (Sydney, Australia)
Jean-Christophe Richard (Angers, France)

  • -

    The worst case scenario: when the circulation stops

                Mypinder S Sekhon (Vancouver, Canada)

  • -

    Advanced simplification of shock physiology

                Sara Crager (Los Angeles, United States)

  • -

    A target MAP of at least 65 mmHg is often excessive

                Giovanni Landoni (Milan, Italy)

  • -

    Perfusion pressure is what counts

                Ashish K Khanna (Winston-Salem, United States)

  • -

    Discussion

  • -

    There may be a place for vasodilators

                Matthieu Legrand (San Francisco, United States)

  • -

    Personalized hemodynamic management

                Bernd Saugel (Hamburg, Germany)

  • -

    The relationship between peripheral circulation and organ perfusion

                Jan Bakker (New York, United States)

  • -

    Discussion

  • -

    Does microcirculatory monitoring have a future?

                Jacques  Duranteau (Le Kremlin-Bicêtre, France)

  • -

    How relevant is venous congestion

                Daniel  De Backer (Braine l´Alleud, Belgium)

  • -

    Is metabolic acidosis good or bad?

                Tomoko Fujii (Tokyo, Japan)

  • -

    Discussion

-
            Pro-con debate Silver Hall Morning (CET)

            IS FEVER REALLY HARMFUL AFTER CARDIAC ARREST? 

            Moderator(s):  Shawniqua Williams Roberson (Nashville, United States)

  • -

    Is fever really harmful after cardiac arrest?

                PRO: Markus Skrifvars (Helsinki, Finland)

                CON: Fabio S Taccone (Brussels, Belgium)

-
            Standard presentation Silver Hall Afternoon (CET)

            NON-INVASIVE RESPIRATORY SUPPORT

            Moderator(s):  Laurent Brochard (Toronto, Canada)
Sara Crager (Los Angeles, United States)

  • -

    HFNO as support or treatment for ARDS?

                Michelle N Gong (New York, United States)

  • -

    HFNO: higher flow is not always better

                Oriol Roca (Sabadell, Spain)

  • -

    Don´t forget CPAP

                Alexandre Demoule (Paris, France)

  • -

    Discussion

  • -

    Helmet or mask?

                Domenico Luca Grieco (Rome, Italy)

  • -

    Use on the general ward?

                Giovanni Landoni (Milan, Italy)

  • -

    We need a personalized approach

                Bhakti Patel (Chicago, United States)

  • -

    Discussion

  • -

    Break

-
            Standard presentation Silver Hall Afternoon (CET)

            ENDOTRACHEAL INTUBATION: WHEN AND HOW?

            Moderator(s):  V Marco Ranieri (Bologna, Italy)
Arnaud Thille (Poitiers, France)

  • -

    Guidelines don´t guide optimal timing

                Edward Schenck (New York, United States)

  • -

    When? Ask the patient!

                Alexandre Demoule (Paris, France)

  • -

    Videolaryngoscopy should be the standard in the critically ill

                Sheila N Myatra (Mumbai, India)

  • -

    Be prepared for a difficult case

                Sara Crager (Los Angeles, United States)

  • -

    Predicting post-intubation hypotension: crashers vs. Drifters

                Alexander Vlaar (Amsterdam, Netherlands)

  • -

    Discussion

-
            Pro-con debate Silver Hall Afternoon (CET)

            THROMBOEMBOLISM PREVENTION

            Moderator(s):  Jacques  Duranteau (Le Kremlin-Bicêtre, France)

  • -

    Thromboembolism prevention

                PRO: Beverley Hunt (London, United Kingdom)

                CON: Mervyn Singer (London, United Kingdom)

-
            Standard presentation 100 Hall Morning (CET)

            TRANSFUSION

            Moderator(s):  Pierre Bouzat (Grenoble, France)
Elizabeth Wilcox (Edmonton, Canada)

  • -

    How red blood cells contribute to hemostasis

                Beverley Hunt (London, United Kingdom)

  • -

    Update on worldwide practices

                Alexander Vlaar (Amsterdam, Netherlands)

  • -

    We have become too restrictive

                Marek Mirski (Baltimore, United States)

  • -

    We need different RCTs

                Jean-Louis Vincent (Brussels, Belgium)

  • -

    Discussion

  • -

    Optimal transfusion strategy in burns

                Tina Palmieri (Sacramento, United States)

  • -

    Optimal transfusion strategy in TBI

                Alexis Turgeon (Québec City, Canada)

  • -

    Indications for platelet transfusions

                Alexander Vlaar (Amsterdam, Netherlands)

  • -

    Discussion

-
            Standard presentation 100 Hall Morning (CET)

            FLUID RESUSCITATION

            Moderator(s):  Stéphane Gaudry (Bobigny, France)
Gianluca  Villa (Florence, Italy)

  • -

    What do you mean by ´fluid overload`?

                Jean-Louis Vincent (Brussels, Belgium)

  • -

    In whom should we predict fluid responsiveness?

                Xavier Monnet (Le Kremlin-Bicêtre, France)

  • -

    Being fluid responsive can be good for the patient

                Jan Bakker (New York, United States)

  • -

    Navigating between inadequate perfusion and hypervolemia

                Maurizio  Cecconi (Milan, Italy)

  • -

    Closed loop resuscitation and intelligent clinical decision support are the future

                Michael R Pinsky (Pittsburgh, United States)

  • -

    Discussion

-
            Standard presentation 100 Hall Afternoon (CET)

            NEUROMONITORING

            Moderator(s):  Victoria McCredie (Toronto, Canada)
Ary Serpa Neto (Armadale, Australia)

  • -

    Automated pupillometry

                Giuseppe Citerio (Monza, Italy)

  • -

    EEG could be used more widely

                Shawniqua Williams Roberson (Nashville, United States)

  • -

    Non-invasive assessment of brain compliance

                Fabio S Taccone (Brussels, Belgium)

  • -

    Look at ICP waveforms

                Geert  Meyfroidt (Leuven, Belgium)

  • -

    Discussion

  • -

    Brain oxygen pressure for everyone?

                Pierre Bouzat (Grenoble, France)

  • -

    Multimodal monitoring

                Mauro Oddo (Lausanne, Switzerland)

  • -

    The role of biomarkers

                Shawniqua Williams Roberson (Nashville, United States)

  • -

    Data science to integrate all this

                Soojin Park (New York, United States)

  • -

    Discussion

-
            Standard presentation 100 Hall Afternoon (CET)

            RENAL REPLACEMENT THERAPY

            Moderator(s):  Hernando Gomez (Pittsburgh, United States)
Axel Nierhaus (Hamburg, Germany)

  • -

    Regional practice variation

                Rinaldo Bellomo (Melbourne, Australia)

  • -

    The basic questions to raise

                Gianluca  Villa (Florence, Italy)

  • -

    A fresh look at citrate

                Patrick Honoré (Yvoir, Belgium)

  • -

    Discussion

  • -

    Hybrid therapy: for which patients?

                Stéphane Gaudry (Bobigny, France)

  • -

    Optimal dosing

                Tomoko Fujii (Tokyo, Japan)

  • -

    Thermoregulation as a physiologic variable during hemodialysis

                Peter Pickkers (Nijmegen, Netherlands)

  • -

    Discussion

-
            Standard presentation 400 Hall Morning (CET)

            CLINICAL TRIALS

            Moderator(s):  Peter Pickkers (Nijmegen, Netherlands)
Christopher Rugg (Innsbruck, Austria)

  • -

    Let´s do a scientometric analysis first

                Leo Anthony Celi (Cambridge, United States)

  • -

    Diversity could be improved

                Jeremy Beitler (New York, United States)

  • -

    Trials for precision medicine are coming

                Lennie Derde (Utrecht, Netherlands)

  • -

    How can we validate an AI system?

                Matthieu Komorowski (London, United Kingdom)

  • -

    Could new statistical methods save negative trials?

                Fernando Zampieri (Edmonton, Canada)

  • -

    Discussion

  • -

    Benefits and limitations of platform trials

                Derek C  Angus (Pittsburgh, United States)

  • -

    Target trial emulation as an alternative to the RCT

                Edward Schenck (New York, United States)

  • -

    Learning from observational studies

                Liesbet De Bus (Ghent, Belgium)

  • -

    Heterogeneity of treatment effect: from clinical trial to clinical practice

                Michelle N Gong (New York, United States)

  • -

    Discussion

-
            Standard presentation 400 Hall Morning (CET)

            HOW I WOULD DESIGN A SUCCESSFUL TRIAL

            Moderator(s):  Mauro Oddo (Lausanne, Switzerland)
Fernando Zampieri (Edmonton, Canada)

  • -

    in TBI

                Alexis Turgeon (Québec City, Canada)

  • -

    in cardiogenic shock

                Jan Belohlavek (Prague, Czech Republic)

  • -

    in ICU nutrition

                Christian Stoppe (Würzburg and Berlin, Germany)

  • -

    in sepsis

                Tom van der Poll (Amsterdam, Netherlands)

  • -

    on early mobilization

                Bhakti Patel (Chicago, United States)

  • -

    Discussion

-
            Standard presentation 400 Hall Afternoon (CET)

            READY FOR THE NEXT PANDEMIC

            Moderator(s):  Matthieu Komorowski (London, United Kingdom)
Vincent Liu (Oakland, United States)

  • -

    Renal replacement therapy in a world of constraints

                Stéphane Gaudry (Bobigny, France)

  • -

    How to prepare the ICU

                Maurizio  Cecconi (Milan, Italy)

  • -

    How to deal with ICU strain

                Elizabeth Wilcox (Edmonton, Canada)

  • -

    Discussion

  • -

    We could better define who should be put on ECMO

                Alain Combes (Paris, France)

  • -

    Research organization should be ready

                John C Marshall (Toronto, Canada)

  • -

    We should have pop-up beds and staff

                Lennie Derde (Utrecht, Netherlands)

  • -

    Discussion

  • -

    Break

-
            Standard presentation 400 Hall Afternoon (CET)

            MIND THE GUT

            Moderator(s):  Tina Palmieri (Sacramento, United States)
Julia  Wendon (London, United Kingdom)

  • -

    Early diagnosis of acute mesenteric ischemia

                Annika  Reintam Blaser (Tartu, Estonia)

  • -

    How to protect the gut in critical illness

                Craig M Coopersmith (Atlanta, United States)

  • -

    The gut microbiome: an organ of immune homeostasis

                John C Marshall (Toronto, Canada)

  • -

    Intraabdominal infections: myths and common beliefs

                Philippe Montravers (Paris, France)

  • -

    Probiotics: yes or no?

                Evangelos Giamarellos–Bourboulis (Athens, Greece)

  • -

    Discussion

-
            Tutorial 400 Hall Afternoon (CET)
  • -

    Basic genomics for the intensivist

                Anthony  McLean (Sydney, Australia)

-
            Standard presentation Panoramic Room Morning (CET)

            QUALITY OF CARE

            Moderator(s):  Elie Azoulay (Paris, France)
Chiara Robba (Genoa, Italy)

  • -

    We should be better at preventing ischemic and hypoxic complications

                Marek Mirski (Baltimore, United States)

  • -

    How to decrease human errors

                Axel Nierhaus (Hamburg, Germany)

  • -

    Do we need cardiac arrest centers?

                Markus Skrifvars (Helsinki, Finland)

  • -

    Learning health systems: Can they work?

                Derek C  Angus (Pittsburgh, United States)

  • -

    How to apply the results of trials to individual patient decisions

                John C Marshall (Toronto, Canada)

  • -

    Discussion

  • -

    Break

-
            Standard presentation Panoramic Room Morning (CET)

            REASSESSING ARDS

            Moderator(s):  John J Marini (St Paul, United States)
Antoine Vieillard–Baron (Boulogne-Billancourt, France)

  • -

    Do we need new criteria?

                Michelle N Gong (New York, United States)

  • -

    Should we abandon the syndrome?

                V Marco Ranieri (Bologna, Italy)

  • -

    Do patients die of or with ARDS?

                Manu Shankar–Hari (Edinburgh, United Kingdom)

  • -

    Discussion

  • -

    The ´omic` approach to personalized care

                Patricia Rocco (Rio De Janeiro, Brazil)

  • -

    We should assess alveolar host response

                Lieuwe  Bos (Amsterdam, Netherlands)

  • -

    Cardiovascular subsets

                Armand  Mekontso Dessap (Créteil, France)

  • -

    Discussion

-
            Clinical Challenges Panoramic Room Afternoon (CET)
  • -

    Colonization by multidrug resistant bacilli: the implications

                Philippe Montravers (Paris, France)

                Andrew  Shorr (Potomac, United States)

-
            Demonstration Panoramic Room Afternoon (CET)
  • -

    Using echocardiography to predict fluid responsiveness

                Paul H Mayo (New York, United States)

                Antoine Vieillard–Baron (Boulogne-Billancourt, France)

-
            Meet the experts Panoramic Room Afternoon (CET)
  • -

    Individualized blood glucose control

                Jan Gunst (Leuven, Belgium)

                Jean-Charles  Preiser (Brussels, Belgium)

-
            Meet the experts Panoramic Room Afternoon (CET)
  • -

    When and how I use beta blockade in sepsis

                Christopher Seymour (Pittsburgh, United States)

                Jean-Louis Vincent (Brussels, Belgium)

-
            Case discussion Panoramic Room Afternoon (CET)

            A PATIENT WITH SEVERE INTRACRANIAL HYPERTENSION

            Moderator(s):  Giuseppe Citerio (Monza, Italy)

  • -

    A patient with severe intracranial hypertension

                Marek Mirski (Baltimore, United States)

-
            Demonstration Panoramic Room Afternoon (CET)
  • -

    ChatGPT can help me to get published

                Aarti Sarwal (Winston Salem, United States)

                Fabio S Taccone (Brussels, Belgium)

-
            Pro-con debate Panoramic Room Afternoon (CET)

            BETA-BLOCKERS IN SEPTIC SHOCK

            Moderator(s):  Michelle N Gong (New York, United States)

  • -

    Beta-blockers in septic shock

                CON: Daniel  De Backer (Braine l´Alleud, Belgium)

                PRO: Michel  Slama (Amiens, France)

-
            Tutorial The Arc Room Morning (CET)
  • -

    How to manage dyspnea

                Alexandre Demoule (Paris, France)

-
            Tutorial The Arc Room Morning (CET)
  • -

    Lung protection focused on tension

                John J Marini (St Paul, United States)

-
            Tutorial The Arc Room Morning (CET)

            VAP PREVENTION


  • -

    VAP prevention

                Despoina  Koulenti (London, United Kingdom)

-
            Tutorial The Arc Room Morning (CET)
  • -

    Patients with cancer: new realities

                Stephen M Pastores (New York, United States)

-
            Tutorial The Arc Room Morning (CET)

            TOXIDROMES


  • -

    Toxidromes

                Heatherlee Bailey (Durham, United States)

-
            Round table The Arc Room Morning (CET)

            HOW CAN WE KEEP OUR STAFF?

            Moderator(s):  Julia  Wendon (London, United Kingdom)

  • -

    How can we keep our staff?

                Elie Azoulay (Paris, France)

                Craig M Coopersmith (Atlanta, United States)

                Sara Crager (Los Angeles, United States)

                Victoria Metaxa (London, United Kingdom)

-
            Round table The Arc Room Afternoon (CET)

            TREATABLE TRAITS VERSUS SUB PHENOTYPES

            Moderator(s):  Joost Wiersinga (Amsterdam, Netherlands)

  • -

    Treatable traits versus sub phenotypes

                Evangelos Giamarellos–Bourboulis (Athens, Greece)

                Patricia Rocco (Rio De Janeiro, Brazil)

                Christopher Seymour (Pittsburgh, United States)

                Manu Shankar–Hari (Edinburgh, United Kingdom)

-
            Round table The Arc Room Afternoon (CET)

            MANAGEMENT OF SEPTIC SHOCK: MORE FLUIDS OR MORE VASOPRESSORS? 

            Moderator(s):  Peter Pickkers (Nijmegen, Netherlands)

  • -

    Management of septic shock: more fluids or more vasopressors?

                Jan Bakker (New York, United States)

                Daniel  De Backer (Braine l´Alleud, Belgium)

                Michael R Pinsky (Pittsburgh, United States)

                Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

-
            Tutorial The Arc Room Afternoon (CET)
  • -

    Non invasive respiratory support

                Lise  Piquilloud (Lausanne, Switzerland)

-
            Tutorial The Arc Room Afternoon (CET)
  • -

    Reversing anticoagulation

                Beverley Hunt (London, United Kingdom)

-
            Tutorial The Arc Room Afternoon (CET)
  • -

    Immunotherapy for sepsis

                Joost Wiersinga (Amsterdam, Netherlands)

-
            Tutorial The Arc Room Afternoon (CET)
  • -

    Management of the organ donor

                Jan Gunst (Leuven, Belgium)

-
            Case discussion Demo box 1 Morning (CET)
  • -

    Abdominal trauma

                Michael Reade (Brisbane, Australia)

                Annika  Reintam Blaser (Tartu, Estonia)

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            Clinical Challenges Demo box 1 Morning (CET)
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    Why doesn´t my patient wake up?

                Cherylee WJ Chang (Durham, United States)

                Victoria McCredie (Toronto, Canada)

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            Demonstration Demo box 1 Morning (CET)
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    Esophageal pressure monitoring

                Jeremy Beitler (New York, United States)

                Lise  Piquilloud (Lausanne, Switzerland)

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            Clinical Challenges Demo box 1 Morning (CET)
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    Why does this perioperative patient develop myocardial injury?

                Michelle Chew (Linköping, Sweden)

                Alexander Vlaar (Amsterdam, Netherlands)

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            Tutorial Demo box 1 Afternoon (CET)
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    Sodium disorders

                Christopher Rugg (Innsbruck, Austria)

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            Clinical Challenges Demo box 1 Afternoon (CET)
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    Toxicities associated with immune checkpoint inhibitors and CAR-T cell therapy

                Elie Azoulay (Paris, France)

                Stephen M Pastores (New York, United States)

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            Demonstration Demo box 1 Afternoon (CET)
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    Individualizing ventilator management in ARDS

                Jeremy Beitler (New York, United States)

                Patricia Rocco (Rio De Janeiro, Brazil)

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            Demonstration Demo box 1 Afternoon (CET)
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    How to monitor capillary refill time in septic shock

                Jan Bakker (New York, United States)

                Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

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            Meet the experts Demo box 2 Morning (CET)
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    Ventilation settings during VV-ECMO

                Alain Combes (Paris, France)

                Giacomo Grasselli (Milan, Italy)

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            Demonstration Demo box 2 Morning (CET)
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    Respiratory drive and effort

                Leo Heunks (Nijmegen, Netherlands)

                Lise  Piquilloud (Lausanne, Switzerland)

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            Demonstration Demo box 2 Morning (CET)
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    Driving pressure

                Luigi Camporota (London, United Kingdom)

                Ewan Goligher (Toronto, Canada)

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            Clinical Challenges Demo box 2 Morning (CET)
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    Management of brain abscess

                Elisa Gouvea Bogossian (Brussels, Belgium)

                Maya  Hites (Brussels, Belgium)

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            Demonstration Demo box 2 Afternoon (CET)
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    Assessing right ventricular function

                Armand  Mekontso Dessap (Créteil, France)

                Michael R Pinsky (Pittsburgh, United States)

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            Clinical Challenges Demo box 2 Afternoon (CET)
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    Using mechanical power at the bedside

                Luigi Camporota (London, United Kingdom)

                John J Marini (St Paul, United States)

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            Clinical Challenges Demo box 2 Afternoon (CET)
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    Perioperative hemodynamics

                Maurizio  Cecconi (Milan, Italy)

                Bernd Saugel (Hamburg, Germany)

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            Meet the experts Demo box 2 Afternoon (CET)
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    How to achieve a negative fluid balance safely

                Daniel  De Backer (Braine l´Alleud, Belgium)

                Xavier Monnet (Le Kremlin-Bicêtre, France)

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            Demonstration Demo box 3 Morning (CET)
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    Challenges in temperature management after cardiac arrest

                Elisa Gouvea Bogossian (Brussels, Belgium)

                Fabio S Taccone (Brussels, Belgium)

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            Clinical Challenges Demo box 3 Morning (CET)
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    Vasopressor therapy

                Ashish K Khanna (Winston-Salem, United States)

                Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

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            Demonstration Demo box 3 Morning (CET)
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    Indirect calorimetry to manage nutrition in critically ill patients

                Horst W Brünner (Fritzlar, Germany)

                Arthur van Zanten (Ede, Netherlands)

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            Demonstration Demo box 3 Morning (CET)
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    Blood purification in severe rhabdomyolysis: novel therapeutic approaches

                Christopher Rugg (Innsbruck, Austria)

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            Demonstration Demo box 3 Afternoon (CET)
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    Helmet and other techniques for noninvasive ventilation

                Domenico Luca Grieco (Rome, Italy)

                Bhakti Patel (Chicago, United States)

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            Demonstration Demo box 3 Afternoon (CET)
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    Importance of perfusion monitoring in the ICU

                Chiara Robba (Genoa, Italy)

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            Case discussion Demo box 3 Afternoon (CET)