Interactive program
Tuesday 19 March 2024
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Welcome
Fabio S Taccone (Brussels, Belgium)
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Report of the Round Table Conference - Artificial intelligence in acute medicine
Azra Bihorac (Gainesville, United States)
Maurizio Cecconi (Milan, Italy)
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Max Harry Weil lecture: Does evidence based medicine limit the practice of personalized medicine?
Sharon Einav-Bromiker (Tel Aviv Jaffo, Israel)
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Let us make a green ICU
Nicole Hunfeld (Rotterdam, Netherlands)
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Host gene expression signatures in children evaluated for sepsis
Luregn Schlapbach (Zürich, Switzerland)
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Effect of lower vs higher oxygenation targets: experience in COVID-19
Frederik Nielsen (Aalborg, Denmark)
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Individualized oxygen targets in mechanically ventilated adults
Kevin Buell (Chicago, United States)
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Safe application of early active mobilisation
Michelle Paton (Clayton, Australia)
EXTRACORPOREAL CO2 REMOVAL
Alain Combes (Paris, France)
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What we have learned so far
Luciano Gattinoni (Göttingen, Germany)
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ECCO2R in ARDS
Luigi Camporota (London, United Kingdom)
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ECCO2R in COPD
V Marco Ranieri (Bologna, Italy)
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Failure of ECCO2R is a failure of technology
Laurent Brochard (Toronto, Canada)
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Discussion
ARTIFICIAL INTELLIGENCE - PRINCIPLES
Christopher Seymour (Pittsburgh, United States)
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Building efficient data driven research
Mauro Oddo (Lausanne, Switzerland)
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Challenges in data collection in the ICU
Leo Anthony Celi (Cambridge, United States)
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Getting into DataScience
Ari Ercole (Cambridge, United Kingdom)
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Discussion
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Natural language processing applied to delirium
Rinaldo Bellomo (Melbourne, Australia)
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Natural Language Processing in Critical Care
Benjamin Shickel (Gainsville, United States)
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Primer on large language models and prompt engineering
Azra Bihorac (Gainesville, United States)
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Discussion
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Sharing is caring - ICUs should share their big data
Paul Elbers (Amsterdam, Netherlands)
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Understanding machine learning methods
Edward Schenck (New York, United States)
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Bridging the ´byte to bedside` gap
Matthieu Komorowski (London, United Kingdom)
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Discussion
CARDIOGENIC SHOCK
Giovanni Landoni (Milan, Italy)
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After cardiac arrest
Markus Skrifvars (Helsinki, Finland)
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The ´congestive heart failure` entity is outdated
Anthony McLean (Sydney, Australia)
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Fulminant myocarditis
Matthieu Schmidt (Paris, France)
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Management of postoperative myocardial injury
Michelle Chew (Linköping, Sweden)
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Discussion
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When to consider ECMO
Jan Belohlavek (Prague, Czech Republic)
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VA-ECMO followed by heart transplantation?
Alain Combes (Paris, France)
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Management of renal failure
Stéphane Gaudry (Bobigny, France)
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Mechanical support
Susanna Price (London, United Kingdom)
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Discussion
ENDOTHELIAL PROTECTION
Despoina Koulenti (London, United Kingdom)
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How to assess endothelial damage
Jan Bakker (Santiago, Chile)
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Gut permeability in sepsis
Craig M Coopersmith (Atlanta, United States)
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Therapies to improve endothelial cell function
Peter Pickkers (Nijmegen, Netherlands)
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Plasma as a resuscitation fluid?
Nicole Juffermans (Amsterdam, Netherlands)
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Discussion
SEPSIS: BACK TO BASICS
Frank van Haren (Sydney, Australia)
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Current thinking on the pathogenesis of sepsis
Joost Wiersinga (Amsterdam, Netherlands)
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Reprogramming metabolism to survive sepsis
Hernando Gomez (Pittsburgh, United States)
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What do we mean by ´dysregulated immune response`?
Manu ShankarHari (Edinburgh, United Kingdom)
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Discussion
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Understanding the neutrophil
John C Marshall (Toronto, Canada)
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New insights into thermoregulation
Peter Pickkers (Nijmegen, Netherlands)
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The influence of alcohol
Craig M Coopersmith (Atlanta, United States)
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Discussion
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How circadian rhythms impact host responses
Elizabeth Wilcox (Edmonton, Canada)
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The important role of the microbiome in sepsis
Joost Wiersinga (Amsterdam, Netherlands)
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We could use immune dysregulation scores
Tom van der Poll (Amsterdam, Netherlands)
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Discussion
THE RENIN-ANGIOTENSIN SYSTEM IN THE ICU
Manu ShankarHari (Edinburgh, United Kingdom)
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How the renin-angiotensin system is affected
Matthieu Legrand (San Francisco, United States)
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How we can manipulate it in critical care
Filippo Annoni (Brussels, Belgium)
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Is renin the new lactate?
Ashish K Khanna (Winston-Salem, United States)
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The future place of angiotensin II
Rinaldo Bellomo (Melbourne, Australia)
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Discussion
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Forget about wet or dry!
Daniel De Backer (Braine l´Alleud, Belgium)
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The limits of diuretic therapy
Marlies Ostermann (London, United Kingdom)
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Optimal ultrafiltration
Jean-Louis Vincent (Brussels, Belgium)
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Fluid removal in heart failure
Stéphane Gaudry (Bobigny, France)
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Discussion
PEEP OPTIMIZATION
Leo Heunks (Nijmegen, Netherlands)
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Should we first assess recruitability?
Luciano Gattinoni (Göttingen, Germany)
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Above the airway opening pressure
Michel Slama (Amiens, France)
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Using EIT
Laurent Brochard (Toronto, Canada)
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Driving pressure
Ewan Goligher (Toronto, Canada)
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Discussion
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Esophageal pressure
Lise Piquilloud (Lausanne, Switzerland)
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Don´t forget the RV
Antoine VieillardBaron (Boulogne-Billancourt, France)
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and the LV
Michel Slama (Amiens, France)
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How to put it all together
Oriol Roca (Sabadell, Spain)
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Discussion
LUNG PROTECTION
Alexander Vlaar (Amsterdam, Netherlands)
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Finding the optimal tidal volume
V Marco Ranieri (Bologna, Italy)
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Driving pressure is more important than tidal volume
Ewan Goligher (Toronto, Canada)
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Is it different for spontaneous vs. mechanical ventilation?
Luciano Gattinoni (Göttingen, Germany)
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Discussion
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Detecting end-tidal hyperinflation
John J Marini (St Paul, United States)
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The role of PEEP
Domenico Luca Grieco (Rome, Italy)
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Rest is best
Patricia Rocco (Rio De Janeiro, Brazil)
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Discussion
POSTANOXIC BRAIN DAMAGE
Mauro Oddo (Lausanne, Switzerland)
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Limiting oxygen
Markus Skrifvars (Helsinki, Finland)
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Moving towards personalized temperature control
Fabio S Taccone (Brussels, Belgium)
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We should target neuroinflammation
Mypinder S Sekhon (Vancouver, Canada)
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Neuroprognostication : mission (im)possible?
Cherylee WJ Chang (Durham, United States)
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Discussion
BLOOD PURIFICATION IN SEPSIS
Stephen M Pastores (New York, United States)
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The rationale
Axel Nierhaus (Hamburg, Germany)
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The problems
Christopher Rugg (Innsbruck, Austria)
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When to combine it with ECMO
Konstanty Szuldrzynski (Warsaw, Poland)
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Discussion
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The right patient
Gianluca Villa (Florence, Italy)
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How biomarkers could help
Silvia Coelho (Amadora, Portugal)
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The therapeutic trial we need
Stéphane Gaudry (Bobigny, France)
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Discussion
HOW I IMAGINE THE FUTURE
Leo Anthony Celi (Cambridge, United States)
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Before hospital admission
Michael R Pinsky (Pittsburgh, United States)
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The emergency room
Heatherlee Bailey (Durham, United States)
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The operating room
Azra Bihorac (Gainesville, United States)
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Discussion
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The ICU
Maurizio Cecconi (Milan, Italy)
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Machine learning systems to inform sepsis resuscitation
Matthieu Komorowski (London, United Kingdom)
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Monitoring for organ failure throughout the hospital
Michelle N Gong (New York, United States)
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Discussion
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Use of viscoelastic testing in massive bleeding
PRO: Pierre Bouzat (Grenoble, France)
CON: Michael Reade (Brisbane, Australia)
FUNGAL INFECTIONS
Bhakti Patel (Chicago, United States)
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Septic shock from candidemia: how often?
Elie Azoulay (Paris, France)
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Fungal infection in the ´immunocompetent` patient
Liesbet De Bus (Ghent, Belgium)
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Emerging Candida species
Thierry Calandra (Lausanne, Switzerland)
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Discussion
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Antifungal dose adjustments during CRRT
Patrick Honoré (Yvoir, Belgium)
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Antimicrobial and antifungal stewardship: are they different?
Despoina Koulenti (London, United Kingdom)
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Biomarkers to guide therapy
Joost Wiersinga (Amsterdam, Netherlands)
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Discussion
UPDATE ON SEPSIS BIOMARKERS
Lieuwe Bos (Amsterdam, Netherlands)
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Novel infection diagnostics
Mervyn Singer (London, United Kingdom)
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Are they ready for routine use?
Jan De Waele (Ghent, Belgium)
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They can help to identify sepsis in the presence of liver failure
Julia Wendon (London, United Kingdom)
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Discussion
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Bacterial or viral infection: consult the immune response
Evangelos GiamarellosBourboulis (Athens, Greece)
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Genomic damage signals in sepsis
Edward Schenck (New York, United States)
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Novel sepsis markers
Andrew Shorr (Potomac, United States)
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How biomarkers can guide the duration of antimicrobial therapy
Jan De Waele (Ghent, Belgium)
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Discussion
EARLY MOBILIZATION
Fernando Zampieri (Edmonton, Canada)
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What is early?
Bhakti Patel (Chicago, United States)
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Recent trials showed no benefit
Leo Heunks (Nijmegen, Netherlands)
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The effect of exercise dosage on outcomes
Michelle Paton (Clayton, Australia)
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Mobilization during ECMO: a bit too much?
Matthieu Schmidt (Paris, France)
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Discussion
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Heat stroke
Heatherlee Bailey (Durham, United States)
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Prescription of antibiotics during CRRT
Tomoko Fujii (Tokyo, Japan)
WORKING TOGETHER
Arthur van Zanten (Ede, Netherlands)
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Optimal organization
Axel Nierhaus (Hamburg, Germany)
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The important role of a pharmacist
Nicole Hunfeld (Rotterdam, Netherlands)
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How to retain your staff
Elie Azoulay (Paris, France)
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How to keep everyone happy
Julia Wendon (London, United Kingdom)
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Discussion
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How to lead successful rounds
Craig M Coopersmith (Atlanta, United States)
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How to learn at the bedside
Mervyn Singer (London, United Kingdom)
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How to develop research in the ICU
Mauro Oddo (Lausanne, Switzerland)
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Expectations from the new generation
Sara Crager (Los Angeles, United States)
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Discussion
MONITORING THE MICROCIRCULATION IN THE SURGICAL PATIENT
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Monitoring the microcirculation in the surgical patient
PRO: Jacques Duranteau (Le Kremlin-Bicętre, France)
CON: Bernd Saugel (Hamburg, Germany)
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Practical prone positioning
Luigi Camporota (London, United Kingdom)
Giacomo Grasselli (Milan, Italy)
Matthieu Schmidt (Paris, France)
Jean-Louis Teboul (Le Kremlin-Bicętre, France)
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The need to monitor cardiac output
Daniel De Backer (Braine l´Alleud, Belgium)
Xavier Monnet (Le Kremlin-Bicętre, France)
Michael R Pinsky (Pittsburgh, United States)
Bernd Saugel (Hamburg, Germany)
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Pathophysiology of sepsis associated renal failure
Hernando Gomez (Pittsburgh, United States)
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Pathophysiology of brain trauma
Marek Mirski (Baltimore, United States)
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Lessons learned from recent trials of ICU nutrition
Christian Stoppe (Würzburg and Berlin, Germany)
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Intrabdominal compartment syndrome
Philippe Montravers (Paris, France)
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Everything you´ve always wanted to know about hemodynamic physiology
Xavier Monnet (Le Kremlin-Bicętre, France)
Michael R Pinsky (Pittsburgh, United States)
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Optimal antibiotic therapy
Maya Hites (Brussels, Belgium)
Andrew Shorr (Potomac, United States)
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Withdrawal of life-sustaining therapies in the patient with acute brain injury
Victoria McCredie (Toronto, Canada)
Alexis Turgeon (Québec City, Canada)
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Is this patient brain ´dead`?
Cherylee WJ Chang (Durham, United States)
Giuseppe Citerio (Monza, Italy)
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Urgent echo in cardiogenic shock
Anthony McLean (Sydney, Australia)
Susanna Price (London, United Kingdom)
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How would you act with no monitoring device?
Xavier Monnet (Le Kremlin-Bicętre, France)
Sheila N Myatra (Mumbai, India)
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Measurement of mean systemic filling pressure at the bedside
Paul H Mayo (New York, United States)
Michael R Pinsky (Pittsburgh, United States)
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Appropriate use of novel antifungal agents
Thierry Calandra (Lausanne, Switzerland)
Philippe Montravers (Paris, France)
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How to assess arterial tone at the bedside
Michael R Pinsky (Pittsburgh, United States)
Jean-Louis Teboul (Le Kremlin-Bicętre, France)
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What hemodynamic monitoring in this patient?
Xavier Monnet (Le Kremlin-Bicętre, France)
Bernd Saugel (Hamburg, Germany)
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How to feed
Jan Gunst (Leuven, Belgium)
Emma Ridley (Melbourne, Australia)
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Extubation failure in the ICU
Domenico Luca Grieco (Rome, Italy)
Arnaud Thille (Poitiers, France)
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Optimal blood pressure in stroke
Jacques Duranteau (Le Kremlin-Bicętre, France)
Alexis Turgeon (Québec City, Canada)
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The dying process
Victoria Metaxa (London, United Kingdom)
Jean-Louis Vincent (Brussels, Belgium)
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Coping with resistant bacteria
Despoina Koulenti (London, United Kingdom)
Andrew Shorr (Potomac, United States)
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Why does this patient with cancer develop renal failure
Victoria Metaxa (London, United Kingdom)
Marlies Ostermann (London, United Kingdom)
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A patient with refractory intracranial hypertension
Michael Reade (Brisbane, Australia)
Fabio S Taccone (Brussels, Belgium)
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ARDS in a TBI patient
Chiara Robba (Genoa, Italy)
Fabio S Taccone (Brussels, Belgium)
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A patient with severe hypoxemia in the absence of ECMO
V Marco Ranieri (Bologna, Italy)
Oriol Roca (Sabadell, Spain)
Wednesday 20 March 2024
ARTIFICIAL INTELLIGENCE - APPLICATIONS
Azra Bihorac (Gainesville, United States)
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Dynamic individualised prediction
Ari Ercole (Cambridge, United Kingdom)
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AI for continuous acuity prediction in the ICU
Benjamin Shickel (Gainsville, United States)
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Prognostication: we can do better than scores
Massimiliano Greco (Milan, Italy)
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Discussion
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AI for all in sepsis?
Christopher Seymour (Pittsburgh, United States)
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AI for early sepsis detection: A word of caution
Joost Wiersinga (Amsterdam, Netherlands)
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AI for expert clinical support.
Hernando Gomez (Pittsburgh, United States)
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Discussion
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AI in neurocritical care
Soojin Park (New York, United States)
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AI in perioperative medicine
Elena Bignami (Parma, Italy)
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Is AI the new ICU resident?
Geert Meyfroidt (Leuven, Belgium)
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Building workforce capacity to integrate it into practice
Vincent Liu (Oakland, United States)
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Discussion
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The interface of AI and RCTs
Derek C Angus (Pittsburgh, United States)
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Building capacity in AI among the next generation of ICU clinicians
Leo Anthony Celi (Cambridge, United States)
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We must stay in control
Sharon Einav-Bromiker (Tel Aviv Jaffo, Israel)
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however the staff numbers will be affected
Paul Elbers (Amsterdam, Netherlands)
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Discussion
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Disseminated intra-vascular coagulation: an update
Jerrold Levy (Durham, United States)
IMPROVING VASOPRESSOR USE
Susanna Price (London, United Kingdom)
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When is arterial pressures too low?
Marek Mirski (Baltimore, United States)
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Early administration of norepinephrine in patients with septic shock: yes, but why?
Jean-Louis Teboul (Le Kremlin-Bicętre, France)
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What about vasopressin?
Jacques Duranteau (Le Kremlin-Bicętre, France)
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What about angiotensin-II?
Giovanni Landoni (Milan, Italy)
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Discussion
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Vasopressin and/or angiotensin-II: a practical approach
Arthur van Zanten (Ede, Netherlands)
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Would a venous vasopressor benefit?
Ashish K Khanna (Winston-Salem, United States)
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Don´t forget the heart
Michel Slama (Amiens, France)
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Discussion
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Resuscitation
Aarti Sarwal (Winston Salem, United States)
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Brain
Fabio S Taccone (Brussels, Belgium)
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Heart
Antoine VieillardBaron (Boulogne-Billancourt, France)
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Abdomen
Pierre Bouzat (Grenoble, France)
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Discussion
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Lung
Paul H Mayo (New York, United States)
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Lung ultrasound for phenotyping of ARDS
Lieuwe Bos (Amsterdam, Netherlands)
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´Ultranurse`: teaching point of care ultrasound to ICU nurses
Paul Elbers (Amsterdam, Netherlands)
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Discussion
SEPSIS MANAGEMENT
Mervyn Singer (London, United Kingdom)
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Phoenix sepsis criteria: small or big step forward?
Luregn Schlapbach (Zürich, Switzerland)
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Early risk assessment
Evangelos GiamarellosBourboulis (Athens, Greece)
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Should fever be treated?
Frank van Haren (Sydney, Australia)
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Source control at 4 am rather than 8 am
Jan De Waele (Ghent, Belgium)
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Artificial intelligence in infection management
Thierry Calandra (Lausanne, Switzerland)
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Discussion
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Artificial intelligence in cardiorespiratory resuscitation
Michael R Pinsky (Pittsburgh, United States)
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Past history of heart failure: does it matter?
Christopher Seymour (Pittsburgh, United States)
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The importance of left and right ventricular functions
Michelle Chew (Linköping, Sweden)
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Beta-stimulation vs. beta-blockade
Michel Slama (Amiens, France)
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Challenges in resource-limited settings
Sheila N Myatra (Mumbai, India)
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Discussion
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Break
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Update on paediatric critical care trials
Luregn Schlapbach (Zürich, Switzerland)
OPTIMIZING ANTIBIOTIC THERAPY
Christian Stoppe (Würzburg and Berlin, Germany)
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New guidelines
Mervyn Singer (London, United Kingdom)
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Antibiotic stewardship should be improved in the emergency room
Heatherlee Bailey (Durham, United States)
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Optimal empirical antimicrobial therapy
Liesbet De Bus (Ghent, Belgium)
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Discussion
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Multiresistant pathogens: the optimal strategy
Philippe Montravers (Paris, France)
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Continuous infusion of betalactam antibiotics finally there?
Jan De Waele (Ghent, Belgium)
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What about meropenem infusions?
Maya Hites (Brussels, Belgium)
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Discussion
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Antibiotics for how long?
Joost Wiersinga (Amsterdam, Netherlands)
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Early switch to oral antibiotics is the way to go
Thierry Calandra (Lausanne, Switzerland)
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Novel antibiotics in the ICU
Andrew Shorr (Potomac, United States)
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Discussion
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Upsurge in invasive group A streptococcal infections
Maya Hites (Brussels, Belgium)
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Multiresistant pathogens: have we already entered the post-antibiotic era?
Despoina Koulenti (London, United Kingdom)
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SDD: Dutch hobby or standard of care?
Lennie Derde (Utrecht, Netherlands)
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SDD does improve outcomes
Jan De Waele (Ghent, Belgium)
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Discussion
SHOCK: THE BASICS
Jean-Christophe Richard (Angers, France)
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The worst case scenario: when the circulation stops
Mypinder S Sekhon (Vancouver, Canada)
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Advanced simplification of shock physiology
Sara Crager (Los Angeles, United States)
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A target MAP of at least 65 mmHg is often excessive
Giovanni Landoni (Milan, Italy)
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Perfusion pressure is what counts
Ashish K Khanna (Winston-Salem, United States)
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Discussion
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There may be a place for vasodilators
Matthieu Legrand (San Francisco, United States)
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Personalized hemodynamic management
Bernd Saugel (Hamburg, Germany)
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The relationship between peripheral circulation and organ perfusion
Jan Bakker (Santiago, Chile)
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Discussion
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Does microcirculatory monitoring have a future?
Jacques Duranteau (Le Kremlin-Bicętre, France)
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How relevant is venous congestion
Daniel De Backer (Braine l´Alleud, Belgium)
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Is metabolic acidosis good or bad?
Tomoko Fujii (Tokyo, Japan)
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Discussion
IS FEVER REALLY HARMFUL AFTER CARDIAC ARREST?
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Is fever really harmful after cardiac arrest?
PRO: Markus Skrifvars (Helsinki, Finland)
CON: Fabio S Taccone (Brussels, Belgium)
NON-INVASIVE RESPIRATORY SUPPORT
Sara Crager (Los Angeles, United States)
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HFNO as support or treatment for ARDS?
Michelle N Gong (New York, United States)
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HFNO: higher flow is not always better
Oriol Roca (Sabadell, Spain)
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Don´t forget CPAP
Alexandre Demoule (Paris, France)
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Discussion
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Helmet or mask?
Domenico Luca Grieco (Rome, Italy)
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Use on the general ward?
Giovanni Landoni (Milan, Italy)
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We need a personalized approach
Bhakti Patel (Chicago, United States)
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Discussion
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Break
ENDOTRACHEAL INTUBATION: WHEN AND HOW?
Arnaud Thille (Poitiers, France)
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Guidelines don´t guide optimal timing
Edward Schenck (New York, United States)
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When? Ask the patient!
Alexandre Demoule (Paris, France)
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Videolaryngoscopy should be the standard in the critically ill
Sheila N Myatra (Mumbai, India)
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Be prepared for a difficult case
Sara Crager (Los Angeles, United States)
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Predicting post-intubation hypotension: crashers vs. Drifters
Alexander Vlaar (Amsterdam, Netherlands)
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Discussion
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Thromboembolism prevention
PRO: Beverley Hunt (London, United Kingdom)
CON: Mervyn Singer (London, United Kingdom)
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How red blood cells contribute to hemostasis
Beverley Hunt (London, United Kingdom)
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Update on worldwide practices
Alexander Vlaar (Amsterdam, Netherlands)
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We have become too restrictive
Marek Mirski (Baltimore, United States)
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We need different RCTs
Jean-Louis Vincent (Brussels, Belgium)
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Discussion
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Optimal transfusion strategy in burns
Tina Palmieri (Sacramento, United States)
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Optimal transfusion strategy in TBI
Alexis Turgeon (Québec City, Canada)
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Indications for platelet transfusions
Alexander Vlaar (Amsterdam, Netherlands)
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Discussion
FLUID RESUSCITATION
Gianluca Villa (Florence, Italy)
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What do you mean by ´fluid overload`?
Jean-Louis Vincent (Brussels, Belgium)
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In whom should we predict fluid responsiveness?
Xavier Monnet (Le Kremlin-Bicętre, France)
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Being fluid responsive can be good for the patient
Jan Bakker (Santiago, Chile)
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Navigating between inadequate perfusion and hypervolemia
Maurizio Cecconi (Milan, Italy)
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Closed loop resuscitation and intelligent clinical decision support are the future
Michael R Pinsky (Pittsburgh, United States)
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Discussion
NEUROMONITORING
Ary Serpa Neto (Armadale, Australia)
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Automated pupillometry
Giuseppe Citerio (Monza, Italy)
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EEG could be used more widely
Shawniqua Williams Roberson (Nashville, United States)
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Non-invasive assessment of brain compliance
Fabio S Taccone (Brussels, Belgium)
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Look at ICP waveforms
Geert Meyfroidt (Leuven, Belgium)
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Discussion
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Brain oxygen pressure for everyone?
Pierre Bouzat (Grenoble, France)
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Multimodal monitoring
Mauro Oddo (Lausanne, Switzerland)
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The role of biomarkers
Shawniqua Williams Roberson (Nashville, United States)
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Data science to integrate all this
Soojin Park (New York, United States)
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Discussion
RENAL REPLACEMENT THERAPY
Axel Nierhaus (Hamburg, Germany)
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Regional practice variation
Rinaldo Bellomo (Melbourne, Australia)
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The basic questions to raise
Gianluca Villa (Florence, Italy)
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A fresh look at citrate
Patrick Honoré (Yvoir, Belgium)
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Discussion
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Hybrid therapy: for which patients?
Stéphane Gaudry (Bobigny, France)
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Optimal dosing
Tomoko Fujii (Tokyo, Japan)
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Thermoregulation as a physiologic variable during hemodialysis
Peter Pickkers (Nijmegen, Netherlands)
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Discussion
CLINICAL TRIALS
Christopher Rugg (Innsbruck, Austria)
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Let´s do a scientometric analysis first
Leo Anthony Celi (Cambridge, United States)
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Diversity could be improved
Jeremy Beitler (New York, United States)
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Trials for precision medicine are coming
Lennie Derde (Utrecht, Netherlands)
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How can we validate an AI system?
Matthieu Komorowski (London, United Kingdom)
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Could new statistical methods save negative trials?
Fernando Zampieri (Edmonton, Canada)
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Discussion
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Benefits and limitations of platform trials
Derek C Angus (Pittsburgh, United States)
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Target trial emulation as an alternative to the RCT
Edward Schenck (New York, United States)
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Learning from observational studies
Liesbet De Bus (Ghent, Belgium)
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Heterogeneity of treatment effect: from clinical trial to clinical practice
Michelle N Gong (New York, United States)
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Discussion
HOW I WOULD DESIGN A SUCCESSFUL TRIAL
Fernando Zampieri (Edmonton, Canada)
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in TBI
Alexis Turgeon (Québec City, Canada)
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in cardiogenic shock
Jan Belohlavek (Prague, Czech Republic)
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in ICU nutrition
Christian Stoppe (Würzburg and Berlin, Germany)
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in sepsis
Tom van der Poll (Amsterdam, Netherlands)
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on early mobilization
Bhakti Patel (Chicago, United States)
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Discussion
READY FOR THE NEXT PANDEMIC
Vincent Liu (Oakland, United States)
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Renal replacement therapy in a world of constraints
Stéphane Gaudry (Bobigny, France)
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How to prepare the ICU
Maurizio Cecconi (Milan, Italy)
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How to deal with ICU strain
Elizabeth Wilcox (Edmonton, Canada)
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Discussion
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We could better define who should be put on ECMO
Alain Combes (Paris, France)
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Research organization should be ready
John C Marshall (Toronto, Canada)
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We should have pop-up beds and staff
Lennie Derde (Utrecht, Netherlands)
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Discussion
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Break
MIND THE GUT
Julia Wendon (London, United Kingdom)
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Early diagnosis of acute mesenteric ischemia
Annika Reintam Blaser (Tartu, Estonia)
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How to protect the gut in critical illness
Craig M Coopersmith (Atlanta, United States)
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The gut microbiome: an organ of immune homeostasis
John C Marshall (Toronto, Canada)
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Intraabdominal infections: myths and common beliefs
Philippe Montravers (Paris, France)
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Probiotics: yes or no?
Evangelos GiamarellosBourboulis (Athens, Greece)
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Discussion
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Basic genomics for the intensivist
Anthony McLean (Sydney, Australia)
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We should be better at preventing ischemic and hypoxic complications
Marek Mirski (Baltimore, United States)
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How to decrease human errors
Axel Nierhaus (Hamburg, Germany)
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Do we need cardiac arrest centers?
Markus Skrifvars (Helsinki, Finland)
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Learning health systems: Can they work?
Derek C Angus (Pittsburgh, United States)
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How to apply the results of trials to individual patient decisions
John C Marshall (Toronto, Canada)
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Discussion
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Break
REASSESSING ARDS
Antoine VieillardBaron (Boulogne-Billancourt, France)
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Do we need new criteria?
Michelle N Gong (New York, United States)
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Should we abandon the syndrome?
V Marco Ranieri (Bologna, Italy)
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Do patients die of or with ARDS?
Manu ShankarHari (Edinburgh, United Kingdom)
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Discussion
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The ´omic` approach to personalized care
Patricia Rocco (Rio De Janeiro, Brazil)
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We should assess alveolar host response
Lieuwe Bos (Amsterdam, Netherlands)
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Cardiovascular subsets
Armand Mekontso Dessap (Créteil, France)
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Discussion
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Colonization by multidrug resistant bacilli: the implications
Philippe Montravers (Paris, France)
Andrew Shorr (Potomac, United States)
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Using echocardiography to predict fluid responsiveness
Paul H Mayo (New York, United States)
Antoine VieillardBaron (Boulogne-Billancourt, France)
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Individualized blood glucose control
Jan Gunst (Leuven, Belgium)
Jean-Charles Preiser (Brussels, Belgium)
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When and how I use beta blockade in sepsis
Christopher Seymour (Pittsburgh, United States)
Jean-Louis Vincent (Brussels, Belgium)
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A patient with severe intracranial hypertension
Marek Mirski (Baltimore, United States)
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ChatGPT can help me to get published
Aarti Sarwal (Winston Salem, United States)
Fabio S Taccone (Brussels, Belgium)
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Beta-blockers in septic shock
CON: Daniel De Backer (Braine l´Alleud, Belgium)
PRO: Michel Slama (Amiens, France)
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How to manage dyspnea
Alexandre Demoule (Paris, France)
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-
Lung protection focused on tension
John J Marini (St Paul, United States)
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-
VAP prevention
Despoina Koulenti (London, United Kingdom)
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-
Patients with cancer: new realities
Stephen M Pastores (New York, United States)
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-
Toxidromes
Heatherlee Bailey (Durham, United States)
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How can we keep our staff?
Elie Azoulay (Paris, France)
Craig M Coopersmith (Atlanta, United States)
Sara Crager (Los Angeles, United States)
Victoria Metaxa (London, United Kingdom)
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-
Treatable traits versus sub phenotypes
Evangelos GiamarellosBourboulis (Athens, Greece)
Patricia Rocco (Rio De Janeiro, Brazil)
Christopher Seymour (Pittsburgh, United States)
Manu ShankarHari (Edinburgh, United Kingdom)
MANAGEMENT OF SEPTIC SHOCK: MORE FLUIDS OR MORE VASOPRESSORS?
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Management of septic shock: more fluids or more vasopressors?
Jan Bakker (Santiago, Chile)
Daniel De Backer (Braine l´Alleud, Belgium)
Michael R Pinsky (Pittsburgh, United States)
Jean-Louis Teboul (Le Kremlin-Bicętre, France)
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Non invasive respiratory support
Lise Piquilloud (Lausanne, Switzerland)
-
-
Reversing anticoagulation
Beverley Hunt (London, United Kingdom)
-
-
Immunotherapy for sepsis
Joost Wiersinga (Amsterdam, Netherlands)
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Management of the organ donor
Jan Gunst (Leuven, Belgium)
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Abdominal trauma
Michael Reade (Brisbane, Australia)
Annika Reintam Blaser (Tartu, Estonia)
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Why doesn´t my patient wake up?
Cherylee WJ Chang (Durham, United States)
Victoria McCredie (Toronto, Canada)
-
-
Esophageal pressure monitoring
Jeremy Beitler (New York, United States)
Lise Piquilloud (Lausanne, Switzerland)
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-
Why does this perioperative patient develop myocardial injury?
Michelle Chew (Linköping, Sweden)
Alexander Vlaar (Amsterdam, Netherlands)
-
-
Sodium disorders
Christopher Rugg (Innsbruck, Austria)
-
-
Toxicities associated with immune checkpoint inhibitors and CAR-T cell therapy
Elie Azoulay (Paris, France)
Stephen M Pastores (New York, United States)
-
-
Individualizing ventilator management in ARDS
Jeremy Beitler (New York, United States)
Patricia Rocco (Rio De Janeiro, Brazil)
-
-
How to monitor capillary refill time in septic shock
Jan Bakker (Santiago, Chile)
Jean-Louis Teboul (Le Kremlin-Bicętre, France)
-
-
Ventilation settings during VV-ECMO
Alain Combes (Paris, France)
Giacomo Grasselli (Milan, Italy)
-
-
Respiratory drive and effort
Leo Heunks (Nijmegen, Netherlands)
Lise Piquilloud (Lausanne, Switzerland)
-
-
Driving pressure
Luigi Camporota (London, United Kingdom)
Ewan Goligher (Toronto, Canada)
-
-
Management of brain abscess
Elisa Gouvea Bogossian (Brussels, Belgium)
Maya Hites (Brussels, Belgium)
-
-
Assessing right ventricular function
Armand Mekontso Dessap (Créteil, France)
Michael R Pinsky (Pittsburgh, United States)
-
-
Using mechanical power at the bedside
Luigi Camporota (London, United Kingdom)
John J Marini (St Paul, United States)
-
-
Perioperative hemodynamics
Maurizio Cecconi (Milan, Italy)
Bernd Saugel (Hamburg, Germany)
-
-
How to achieve a negative fluid balance safely
Daniel De Backer (Braine l´Alleud, Belgium)
Xavier Monnet (Le Kremlin-Bicętre, France)
-
-
Challenges in temperature management after cardiac arrest
Elisa Gouvea Bogossian (Brussels, Belgium)
Fabio S Taccone (Brussels, Belgium)
-
-
Vasopressor therapy
Ashish K Khanna (Winston-Salem, United States)
Jean-Louis Teboul (Le Kremlin-Bicętre, France)
-
-
Indirect calorimetry to manage nutrition in critically ill patients
Horst W Brünner (Fritzlar, Germany)
Arthur van Zanten (Ede, Netherlands)
-
-
Blood purification in severe rhabdomyolysis: novel therapeutic approaches
Christopher Rugg (Innsbruck, Austria)
-
-
Helmet and other techniques for noninvasive ventilation
Domenico Luca Grieco (Rome, Italy)
Bhakti Patel (Chicago, United States)
-
-
Importance of perfusion monitoring in the ICU
Chiara Robba (Genoa, Italy)